TMEM14A Antibody, HRP conjugated

Code CSB-PA023720LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM14A Polyclonal antibody
Uniprot No.
Target Names
TMEM14A
Alternative Names
TMEM14A; C6orf73; PTD011; Transmembrane protein 14A
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transmembrane protein 14A protein (45-78AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits apoptosis via negative regulation of the mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
Gene References into Functions
  1. these results indicate that TMEM14A has a pro-tumorigenic effect in ovarian cancer cells, suggesting an important role of this protein in ovarian cancer oncogenesis and metastasis. PMID: 26896463
  2. findings show for the first time that TMEM14A inhibits apoptosis by blocking the mitochondrial permeability transition and stabilizing mitochondrial membrane potential PMID: 21723035
Subcellular Location
Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.
Protein Families
TMEM14 family
Tissue Specificity
Expressed at significantly higher levels in ovarian cancer tissues than in normal tissues (at protein level).
Database Links

HGNC: 21076

KEGG: hsa:28978

UniGene: Hs.94896

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